Isabel Rangel Barón: Innate immune memory in the brain shapes neurological disease hallmarks

Innate immune memory in the brain shapes neurological disease hallmarks

Innate immune memory in the brain shapes neurological disease hallmarks, Published online: 11 April 2018; doi:10.1038/s41586-018-0023-4

Peripheral stimuli can induce acute immune training and tolerance in the brain and lead to long-lasting epigenetic reprogramming of microglia; these changes alter pathology in mouse models of stroke and Alzheimer’s pathology .

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